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2026 Publications

• Adenawoola MI, Kipp ZA, Hinds TD Jr, Stec DE. Transforming Toxicity into Therapy: Exploring Bilirubin's Benefits and Its Molecular Role in Cardiac Health and Disease. Biomolecules. 2026 Apr 23;16(5):625. doi: 10.3390/biom16050625. PMID: 42193976; PMCID: PMC13204531.
• Badmus OO, Parrow LD, McGowen KE, Bell L, Greer JR, Cruz MC, Hinds TD Jr, Stec DE. Cardioprotective Effects of 1,3 Butanediol in MASLD via Reversal of Cardiac Lipid Accumulation and Suppression of Cardiac Fibrosis. Int J Mol Sci. 2026 Jun 13;27(12):5354. doi: 10.3390/ijms27125354. PMID: 42353074; PMCID: PMC13299300.
• Bhattarai U, Niu Z, Pan L, He X, Wang D, Orman TC, Wang H, Zeng H, Chen JX, Xu X, Speed JS, Clemmer JS, Hall JE, Chen Y. Genetic inhibition of IL-12β suppresses systolic overload-induced cardiac oxidative stress, inflammation, and heart failure development. Redox Biol. 2026 Apr;91:104082. doi: 10.1016/j.redox.2026.104082. Epub 2026 Feb 11. PMID: 41713222; PMCID: PMC12927108.
• Beeton K, Haskell JP, Mitra D, Taylor EB, Bidwell GL. Optimizing delivery of an anti-cytomegalovirus inhibitory peptide using a cell-penetrating peptide. J Gen Virol. 2026 Jan;107(1):002210. doi: 10.1099/jgv.0.002210. PMID: 41528341; PMCID: PMC12799271.
• Coats LE, Campbell N, Solise D, Chamoun GM, Rawls AZ, Demesa A, Turner T, Zheng B, Alexander BT, LaMarca B. Tumor necrosis factor alpha inhibition improves fetal growth in a rat model of preeclampsia. Placenta. 2026 Mar 25;176:22-30. doi: 10.1016/j.placenta.2026.02.002. Epub 2026 Feb 9. PMID: 41671937; PMCID: PMC13173550.
• Dasinger JH, Alexander BT. Effective mentoring in the academic biomedical sciences: a collaborative effort that takes a village. Adv Physiol Educ. 2026 Mar 1;50(1):158-163. doi: 10.1152/advan.00247.2025. Epub 2025 Dec 18. PMID: 41412570; PMCID: PMC12863053. 10.1152/ajpheart.00047.2026. Epub 2026 Apr 24. PMID: 42030244; PMCID: PMC13188341.
• do Carmo JM, Hall JE, Ladnier E, Dai X, Wang Z, Mouton AJ, Omoto ACM, Jorge L, da Silva AA. Parental obesity exacerbates cognitive dysfunction and cardiac vulnerability in offspring of an Alzheimer disease model. Am J Physiol Heart Circ Physiol. 2026 Jun 1;330(6):H1827-H1840. doi: 10.1152/ajpheart.00047.2026. Epub 2026 Apr 24. PMID: 42030244; PMCID: PMC13188341.
• do Carmo JM, Hall JE, Dai X, Ladnier E, Wang Z, Mouton AJ, da Silva AA. Neonatal hyperoxia exposure does not exacerbate hypertension programmed by maternal obesity. Am J Physiol Regul Integr Comp Physiol. 2026 Jan 1;330(1):R13-R22. doi: 10.1152/ajpregu.00221.2025. Epub 2025 Nov 21. PMID: 41269706; PMCID: PMC12797189.
• Eddy AC, Bakrania BA, Yang W, Rajakumar A, George EM, Granger JP, Rana S. Luteolin decreases sFlt-1 and mean arterial pressure in the RUPP animal model of placental ischemia. Placenta. 2026 Jun 20;182:150-157. doi: 10.1016/j.placenta.2026.06.010. Epub ahead of print. PMID: 42361645.
• Frambes NI, Taylor EB, Sullivan JC, Ryan MJ. Keeping it acid ceramidase: How adiponectin protects in the glomerulus. J Pharmacol Exp Ther. 2026 Jul 27:104979. doi: 10.1016/j.jpet.2026.104979. Epub ahead of print. PMID: 42509125.
• Gao J, Lan T, Xu X, Guo H, Wang S, Zhang P, Polunovsky VA, Sonenberg N, Bitterman PB, Bache RJ, Hu X, Lu Z, Chen Y. 4E-BP inhibition ameliorates heart failure through translational upregulation of SERCA2a and modulation of mitochondrial redox signaling in cardiomyocytes. Redox Biol. 2026 Apr;91:104089. doi: 10.1016/j.redox.2026.104089. Epub 2026 Feb 16. PMID: 41713223; PMCID: PMC12927070.
• Hall JE, Omoto ACM, Hall ME. Is Obesity a Major Driver of Primary Aldosteronism? JACC Basic Transl Sci. 2026 Apr;11(4):101541. doi: 10.1016/j.jacbts.2026.101541. PMID: 42047419; PMCID: PMC13131370.
• Hall JE, Omoto ACM, do Carmo JM, da Silva AA, Mouton AJ, Wang Z, Hall ME. Cardiometabolic regulation by adipocyte-derived leptin and the brain melanocortin system. Clin Sci (Lond). 2026 Jul 15;140(7):1473-1496. doi: 10.1042/CS20250039. PMID: 42340064; PMCID: PMC13305822.
• Hester RL, Musch T, Bodine SC. Advancing Physiology in a Year of Challenge and Change. Physiology (Bethesda). 2026 Mar 1;41(2):102-104. doi: 10.1152/physiol.00003.2026. Epub 2026 Jan 28. PMID: 41605415.
• Islam T, Nemeth Z, Lirette S, Taylor EB, Shi S, Kleyman TR, Drummond HA. Smooth Muscle βENaC Deletion Induces Moderate Hypertension and Renal Injury. Kidney360. 2026 Jul 24. doi: 10.34067/KID.0000001306. Epub ahead of print. PMID: 42497017.
• Konadu B, Logan MK, Cox CK, Edwards KS, Speed JS, Gibert Y. Transient fetal hyperglycemia reprograms adipogenesis, lipogenesis, and insulin signaling in zebrafish. Biomed Pharmacother. 2026 Jun;199:119445. doi: 10.1016/j.biopha.2026.119445. Epub 2026 Apr 29. PMID: 42061134.
• Mallette JH, Speed JS, Lirette ST, Moore D, Clemmer JS. Responses to GLP-1RA in White and Black Adults With Obesity: Insights From Generalized Additive Mixed Models of EHR Data. Obesity (Silver Spring). 2026 Apr 1:10.1002/oby.70180. doi: 10.1002/oby.70180. Epub ahead of print. PMID: 41919489; PMCID: PMC13191755.
• Martinez GJ, Stec DE, Hinds TD Jr. Glucocorticoid resistance-induced inflammation drives cardiovascular-kidney-metabolic (CKM) syndrome pathophysiology. Trends Endocrinol Metab. 2026 Jun 4:S1043-2760(26)00123-2. doi: 10.1016/j.tem.2026.05.004. Epub ahead of print. PMID: 42242931; PMCID: PMC13245366.
• Omoto ACM, Vechetti I, do Carmo JM, Wang Z, Mouton AJ, Young JC, Dai X, Ladnier EC, Zenum SC, Tosta OES, Romeiro L, Hamby M, Li X, Spitz R, Richards AM, Johns CH, Goergen CJ, da Silva AA, Hall JE. Leptin Activates Brain-BAT-Heart Crosstalk to Promote Cardiac Protection. Circ Res. 2026 Feb 4:10.1161/CIRCRESAHA.125.326878. doi: 10.1161/CIRCRESAHA.125.326878. Epub ahead of print. PMID: 41636042; PMCID: PMC12875649.
• Pauss SN, Chhabra KH, Stec DE, Gipson CD, Hinds TD Jr. Hepatic neurons and metabolically induced liver dysfunction. Nat Rev Endocrinol. 2026 Jun 19. doi: 10.1038/s41574-026-01270-9. Epub ahead of print. PMID: 42321413.
• O'Quinn KR, Wright CB, Khan M, Spitz RW, Rouhi N, Morato JG, Vidal PA, Omoto ACM, da Silva AA, do Carmo JM, Wang Z, Li X, Hall JE, Mouton AJ. Distinct immunometabolic signatures of type 1 versus type 2 diabetes in a murine model of myocardial infarction. Cardiovasc Diabetol. 2026 Feb 8;25(1):84. doi: 10.1186/s12933-026-03099-y. PMID: 41656217; PMCID: PMC12983673.
• Rhymes JA, Mendoza LD, Sandifer JD, Sullivan JC, Ryan MJ, Taylor EB. Caloric Restriction Decreases Autoimmune Disease Activity and Lowers Blood Pressure in an Experimental Model of Systemic Lupus Erythematosus. Am J Physiol Renal Physiol. 2026 Jul 25. doi: 10.1152/ajprenal.00122.2026. Epub ahead of print. PMID: 42501343.
• Shi S, Whelan SCM, Szekely KG, Kashlan OB, Drummond H, Kleyman TR. Acid-sensing ion channel 2a assembles with epithelial Na⁺ channel β and γ subunits to form mechanosensitive ion channels. J Biol Chem. 2026 Jul;302(7):113151. doi: 10.1016/j.jbc.2026.113151. Epub 2026 May 14. PMID: 42140436; PMCID: PMC13273826.
• Souza GMPR, Thakkalapally H, Berry FE, Wisniewski LF, Atongazi UM, Stornetta DS, Abbott SBG. Control of Blood Pressure Variability Across Behavioral States by Brainstem Adrenergic Neurons. Circ Res. 2026 Feb 13;138(4):e326792. doi: 10.1161/CIRCRESAHA.125.326792. Epub 2026 Jan 13. PMID: 41527820; PMCID: PMC12994584.
• Wahba S, Badmus OO, Wasson AR, Parrow LD, Abdel-Hakeem EA, Ragy MM, Ibrahim HM, Stec DE. Sex dimorphism in the cardiovascular responses to d-galactose-induced accelerated aging: effects of HO-1 modulation. Geroscience. 2026 Mar 15. doi: 10.1007/s11357-026-02165-3. Epub ahead of print. PMID: 41832379.
• Wahba S, Badmus OO, Wasson AR, Abdel-Hakeem EA, Ragy MM, Ibrahim HM, Rüedi-Bettschen D, Stec DE. Behavior and Musculoskeletal Effects of Chronic D-Galactose Treatment in Mice: Role of Heme Oxygenase-1. Biomolecules. 2026 Apr 8;16(4):548. doi: 10.3390/biom16040548. PMID: 42072668; PMCID: PMC13113933.
• Yue W, Xu Y, Weng X, Wang D, Shang L, Jiang H, Weir EK, Liu J, Xu Y, Che W, Chen Y. Systolic pressure overload caused pulmonary oxidative stress, vessel remodeling and severe microvascular thrombosis in CD40 knockout mice through promoting platelet aggregation. Redox Biol. 2026 May;92:104122. doi: 10.1016/j.redox.2026.104122. Epub 2026 Mar 21. PMID: 41905182; PMCID: PMC13054292.